Кафедра фізіології, медичної біології та біологічної фізики

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Browsing Кафедра фізіології, медичної біології та біологічної фізики by Author "Shesterina, Daria"

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    MODIFICATIONS OF LOWER LIMBS CENTRAL AND PERIPHERAL HEMODYNAMICS DUE TO INTERMITTENT PNEUMATIC COMPRESSION EFFECTS
    (SÉRIE“Lékařské vědy”, 2023-03-26) Palamarchuk, Andrii; Shesterina, Daria
    Abstract. High prevalence of cardiovascular diseases [1] implies continuous improvement of noninvasive physical techniques particularly perfectioning of compression therapy techniques [2]. Intermittent pneumatic compression (IPC) widely used thought multipurpose physical rehabilitation in vascular surgery, dermatologic surgery, and sport medicine (Wesley C. et al. 2015). Compression therapy (CT) is an established treatment method with very low rate of complications in research various facets of vascular and skeletal muscle physiology [3]. However, despite the widely accepted usage of IPC, the exact consensus on the IPC pressure and time parameters is not established yet. The study was aimed to evaluate hemodynamic effects of intermittent pneumatic compression on the lower extremities and identify most effectiveness external pressure parameter and optimal procedure timing. The study was included healthy 30 volunteers, 17+ years of age. Vascular assessment included determination of the resting ankle-brachial pressure index (ABI) and entered into intermittent pneumatic pressure correction program. According of ABI pressures of 40,80, and 100 mmHg, and the procedure time limit at 20 minutes were applied. Outcome was considered succeed if blood pressure was dropped during and after procedure by increasing the expelled blood volume flow during a given period. To investigate the blood flow velocity during IPC, impedance cardio-vasography (ICVG) was implied. A summary of the 20-minute testing with different IPC of pressure indicators in the chambers led to the following outcomes. Correlational analysis of systolic-diastolic index with the maximum value of systolic amplitude manifested minor changes [0,3886±0,02157 (mean ± SD)] from the respective rest value. The amplitude of the systolic wave, which is mainly determined by the pulse blood filling, increases [0,1661±0,02959 mean ± SD)] from the respective rest value that is, the larger the volume of the muscle tissue blood filling per unit time. The increase time of fast blood filling and systolic amplitude for about 15 and 20 minutes of recovery after procedure was observed to be statistically significant (the correlation coefficient is 0.7705). Peaks in the low frequency (LF) ranging from 0.04 Hz to 0.15 Hz is were increase for about 5-10 min in recovery period. The low frequency/high frequency ratio, which consists of the ratio of the powers is used to quantify the sympathovagal balance.IPC devices for prevention hypertension is gradually becoming a standard second-order therapy, for instance, in particular, for patients with a high risk of bleeding. However, further studies for determining a more accurate time of inflation and deflation in the chambers of IPC devices are required